Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals.

ABSTRACT:

Importance

In October 2015, the Centers for Medicare & Medicaid Services began requiring US hospitals to report adherence to the Severe Sepsis and Septic Shock Early Management Bundle (SEP-1).

Objective

To evaluate the association of SEP-1 implementation with sepsis treatment patterns and outcomes in diverse hospitals.

Design, setting, and participants

This retrospective cohort study with interrupted time-series analysis and logistic regression models was conducted among adults admitted to 114 hospitals from October 2013 to December 2017 with suspected sepsis (blood culture orders, ≥2 systemic inflammatory response syndrome criteria, and acute organ dysfunction) within 24 hours of hospital arrival. Data analysis was conducted from September 2020 to September 2021.

SUBMITTER: Rhee C 

PROVIDER: S-EPMC8689388 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature