Respiratory tract infection and risk of bleeding in oral anticoagulant users: self-controlled case series.

ABSTRACT:

Objective

To estimate the association between untreated, community acquired, respiratory tract infections and bleeding in oral anticoagulant users.

Design

Self-controlled case series.

Setting

General practices in England contributing data to the Clinical Practice Research Datalink GOLD.

Participants

1208 adult users of warfarin or direct oral anticoagulants with a general practice or hospital admission record of a bleeding event between January 2010 and December 2019, and a general practice record of a consultation for a community acquired respiratory tract infection for which immediate antibiotics were not prescribed (that is, untreated).

Main outcome measures

Relative incidence of major bleeding and clinically relevant non-major bleeding in the 0-14 da

SUBMITTER: Ahmed H 

PROVIDER: S-EPMC8689396 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature