Supramolecular capture of highly polar amidosquaraine dye in water with nanomolar affinity and large turn-on fluorescence.

ABSTRACT: A supramolecular dye-capture system comprising anionic amidosquaraine guest and macrocyclic tetralactam host exhibits nanomolar affinity and "turn on" visible fluorescence. Utility is demonstrated with a new fluorescent assay for liposome leakage induced by the biomedically important enzyme phospholipase A₂.

SUBMITTER: Dharmarwardana M 

PROVIDER: S-EPMC8689413 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature