Bariatric Surgery and Risk of New-onset Inflammatory Bowel Disease: A Nationwide Cohort Study.

ABSTRACT:

Background and aims

The aim of this study was to examine the risk of new-onset inflammatory bowel disease [IBD] following bariatric surgery.

Methods

We conducted a nationwide population-based prospective cohort study of the entire Danish population 18 to 60 years of age, alive, and residing in Denmark, from 1996 to 2018. Bariatric surgery was included as a time-dependent variable, and Cox proportional hazards regression models were used to estimate hazard ratios [HRs] of IBD. We used a model adjusting for age, sex, and birth cohort and a multifactor-adjusted model additionally including educational status and number of obesity-related comorbidities.

Results

We followed 3 917 843 individuals of whom 15 347 had a bariatric surgery, for development of new-onset IBD. Duri

SUBMITTER: Allin KH 

PROVIDER: S-EPMC8691051 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature