Statins for treatment of chronic liver disease.

ABSTRACT:

Purpose of review

Statins are a class of lipid lower medications used primarily in patients with high-risk cardiovascular disease. Since their development, statins have been considered to be harmful in patients with liver disease, and many of the prescribing information labels consider them to be contraindicated in patients with active liver disease. However, recent studies have shown the contrary, warranting further investigation and discussion. This review aims to describe the latest literature on the mechanism, safety profile and potential benefits of statins use on the natural history of chronic liver disease (CLD) progression and its complications.

Recent findings

A number of recently published studies have added to the existing body of literature supporting the concept

SUBMITTER: Marrache MK 

PROVIDER: S-EPMC8691140 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature