Pelvic lymph node dissection in high-risk prostate cancer.

ABSTRACT:

Introduction

The therapeutic role of pelvic lymph node dissection (PLND) in prostate cancer (PCa) is unknown due to absence of randomized trials.

Objective

to present a critical review on the therapeutic benefits of PLND in high risk localized PCa patients.

Materials and methods

A search of the literature on PLND was performed using PubMed, Cochrane, and Medline database. Articles obtained regarding diagnostic imaging and sentinel lymph node dissection, PLND extension, impact of PLND on survival, PLND in node positive "only" disease and PLND surgical risks were critically reviewed.

Results

High-risk PCa commonly develops metastases. In these patients, the possibility of presenting lymph node disease is high. Thus, extended PLND during radical prostatectomy may

SUBMITTER: Haiquel L 

PROVIDER: S-EPMC8691250 | biostudies-literature | 2022 Jan-Feb

REPOSITORIES: biostudies-literature