Opioid Analgesics and Persistent Pain After an Acute Pain Emergency Department Visit: Evidence from a Cohort of Suspected Urolithiasis Patients.

ABSTRACT:

Background

Severe acute pain is still commonly treated with opioid analgesics in the United States, but this practice could prolong the duration of pain.

Objectives

Estimate the risk of experiencing persistent pain after opioid analgesic use after emergency department (ED) discharge among patients with suspected urolithiasis.

Methods

We analyzed data collected for a longitudinal, multicenter clinical trial of ED patients with suspected urolithiasis. We constructed multilevel models to estimate the odds ratios (ORs) of reporting pain at 3, 7, 30, or 90 days after ED discharge, using multiple imputation to account for missing outcome data. We controlled for clinical, demographic, and institutional factors and used weighting to account for the propensity to be prescribed

SUBMITTER: Wentz AE 

PROVIDER: S-EPMC8691537 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature