DHEA and polycystic ovarian syndrome: Meta-analysis of case-control studies.

ABSTRACT:

Background

Polycystic ovarian syndrome is a heterogenous endocrine disorder characterized by irregular menstrual cycles, hirsuitism and polycystic ovaries. It is further complicated by metabolic syndrome, infertility and psychological stress. Although the etiopathogenesis is unclear, many studies have pointed out the role of stress in this syndrome. DHEA, being a stress marker is being used by scientists to compare the stress levels between polycystic ovarian cases and healthy controls. However, the results obtained from previous studies are equivocal.

Objective

To perform meta-analysis and find the association between stress and the syndrome.

Data sources

Relevant data till January 2021 were retrieved from PubMed, Scopus, Embase and Web of Science using MeSH terms.

SUBMITTER: Benjamin JJ 

PROVIDER: S-EPMC8691613 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature