Does microbiological contamination of homografts prior to decontamination affect the outcome after right ventricular outflow tract reconstruction?

ABSTRACT:

Objectives

Homografts are often in short supply. Today, European guidelines recommend that all tissues contaminated by any of 18 different bacteria and fungi be discarded before antibiotic decontamination has been conducted. The tissue bank in Lund uses more liberal protocols: It accepts all microbes prior to decontamination except multiresistant microbes and Pseudomonas species. The aim of this study was to analyse the effect of contamination on the long-term outcome and occurrence of endocarditis in recipients.

Methods

Data were collected on homografts and on recipients of homografts in the right ventricular (RV) outflow tract who were operated on between 1995 and 2018 in Lund. The long-term outcome of recipients was analysed in relation to different types of contamination

SUBMITTER: Axelsson I 

PROVIDER: S-EPMC8691665 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature