Protein Based Biomaterials for Therapeutic and Diagnostic Applications.

ABSTRACT: Proteins are some of the most versatile and studied macromolecules with extensive biomedical applications. The natural and biological origin of proteins offer such materials several advantages over their synthetic counterparts, such as innate bioactivity, recognition by cells and reduced immunogenic potential. Furthermore, proteins can be easily functionalized by altering their primary amino acid sequence and can often be further self-assembled into higher order structures either spontaneously or under specific environmental conditions. This review will feature the recent advances in protein-based biomaterials in the delivery of therapeutic cargo such as small molecules, genetic material, proteins, and cells. First, we will discuss the ways in which secondary structural motifs, the buildin

SUBMITTER: Chu S 

PROVIDER: S-EPMC8691744 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature