Quantification of Arterial and Venous Morphologic Markers in Pulmonary Arterial Hypertension Using CT Imaging.

ABSTRACT:

Background

Pulmonary hypertension is a heterogeneous disease, and a significant portion of patients at risk for it have CT imaging available. Advanced automated processing techniques could be leveraged for early detection, screening, and development of quantitative phenotypes. Pruning and vascular tortuosity have been previously described in pulmonary arterial hypertension (PAH), but the extent of these phenomena in arterial vs venous pulmonary vasculature and in exercise pulmonary hypertension (ePH) have not been described.

Research question

What are the arterial and venous manifestations of pruning and vascular tortuosity using CT imaging in PAH, and do they also occur in ePH?

Study design and methods

A cohort of patients with PAH and ePH and control subjects with a

SUBMITTER: Rahaghi FN 

PROVIDER: S-EPMC8692106 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature