Pre-infection HDL-cholesterol levels and mortality among elderly patients infected with SARS-CoV-2.

ABSTRACT:

Background and aims

Low HDL-cholesterol (HDLc) concentration is associated with a greater risk of infection-related mortality. We wanted to evaluate the relationship between pre-infection HDLc levels and mortality among older patients infected with SARS-Cov-2.

Methods

This is a population-based, cohort study, comprising all individuals residing in Madrid (Spain) born before 1 January 1945, and alive on 31 December 2019. Demographic, clinical, and analytical data were obtained from the primary care electronic clinical records. Confirmed SARS-CoV-2 infection was defined as a positive result in the RT-qPCR or in the antigen test. A death from COVID-19 was defined as that registered in the hospital chart, or as any death occurring in the 15 days following a confirmed SARS-CoV-2

SUBMITTER: Mostaza JM 

PROVIDER: S-EPMC8692242 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature