A mild one-pot synthesis of 2-iminothiazolines from thioureas and 1-bromo-1-nitroalkenes.

ABSTRACT: A mild method to access functionalized 2-iminothiazolines in a facile and efficient manner has been developed. The reaction started from 1,3-disubstituted thioureas and 1-bromo-1-nitroalkenes in the presence of triethylamine in THF and proceeded smoothly in air to afford 2-iminothiazoline derivatives in moderate to good yields.

SUBMITTER: Xu Y 

PROVIDER: S-EPMC8693722 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature