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Novel albumin-binding photothermal agent ICG-IBA-RGD for targeted fluorescent imaging and photothermal therapy of cancer.


ABSTRACT: In this work, we present a novel photothermal agent ICG-IBA-RGD based on albumin-binding strategy for enhanced tumor targeting imaging and photothermal therapy. In vitro and in vivo experiments demonstrated that ICG-IBA-RGD exhibits excellent photothermal conversion capability and high tumor ablation efficiency.

SUBMITTER: Yu C 

PROVIDER: S-EPMC8695055 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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Novel albumin-binding photothermal agent ICG-IBA-RGD for targeted fluorescent imaging and photothermal therapy of cancer.

Yu Cheng C   Xiao Enhua E   Xu Pengfei P   Lin Jingjing J   Hu Linan L   Zhang Jie J   Dai Shengzhen S   Ding Zhuyuan Z   Xiao Yuyang Y   Chen Zhu Z  

RSC advances 20210211 13


In this work, we present a novel photothermal agent ICG-IBA-RGD based on albumin-binding strategy for enhanced tumor targeting imaging and photothermal therapy. <i>In vitro</i> and <i>in vivo</i> experiments demonstrated that ICG-IBA-RGD exhibits excellent photothermal conversion capability and high tumor ablation efficiency. ...[more]

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