Fabrication and characterization of 3D printable nanocellulose-based hydrogels for tissue engineering.

ABSTRACT: Cellulose nanocrystal (CNC)-based hydrogels are considered attractive biomaterials for tissue engineering due to their excellent physicochemical properties. Hydrogels of alginate and gelatin were prepared with or without CNCs and printed using a CELLINK® BIOX 3D bio-printer. The 3D-printed scaffolds were characterized by Fourier transform infrared (FTIR) spectroscopy, Raman spectroscopy, transmission electron microscopy (TEM), and scanning electron microscopy (SEM). Improved mechanical strength was observed in the composite scaffolds compared to the pure polymer scaffolds. Fabricated scaffolds exhibited superior swelling potential; this property is profoundly affected by the CNC content of hydrogels. Biocompatibility of the fabricated scaffolds was monitored in the presence of human bone m

SUBMITTER: Patel DK 

PROVIDER: S-EPMC8695076 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature