The effect of pH and transition metal ions on cysteine-assisted gold aggregation for a distinct colorimetric response.

ABSTRACT: Colorimetric detection is a promising sensing strategy that is applicable to qualitative and quantitative determination of an analyte by monitoring visually detectable color changes with the naked eye. This study explored the cysteine (Cys)-induced aggregation of gold nanoparticles (AuNPs) in order to develop a sensitive colorimetric detection method for Cys. For this purpose, we systematically investigated the colorimetric response of AuNPs to Cys with varying particle sizes and concentrations. The AuNPs with various diameters ranging from 26.5 nm to 58.2 nm were synthesized by the citrate reduction method. When dispersed in water to have the same surface area per unit volume, the smaller AuNPs (26.5 nm) exhibited a more sensitive response to Cys compared to a larger counterpart (46.3 nm)

SUBMITTER: Thuy Nguyen TT 

PROVIDER: S-EPMC8695409 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature