A systematic review of TMS and neurophysiological biometrics in patients with schizophrenia.

ABSTRACT:

Background

Transcranial magnetic stimulation can be combined with electromyography (TMS-EMG) and electroencephalography (TMS-EEG) to evaluate the excitatory and inhibitory functions of the cerebral cortex in a standardized manner. It has been postulated that schizophrenia is a disorder of functional neural connectivity underpinned by a relative imbalance of excitation and inhibition. The aim of this review was to provide a comprehensive overview of TMS-EMG and TMS-EEG research in schizophrenia, focused on excitation or inhibition, connectivity, motor cortical plasticity and the effect of antipsychotic medications, symptom severity and illness duration on TMS-EMG and TMS-EEG indices.

Methods

We searched PsycINFO, Embase and Medline, from database inception to April 2020, for

SUBMITTER: di Hou M 

PROVIDER: S-EPMC8695525 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature