Change of Retinal Vessel Density After Lowering Intraocular Pressure in Ocular Hypertension.

ABSTRACT: Purpose: To investigate the relationship between retinal microvasculature changes and intraocular pressure (IOP) for ocular hypertension (OHT) patients and further assess the factors associated with retinal microcirculation changes. Methods: This was a single-center prospective study designed for OHT patients, which consisted of two visits. After collecting baseline data of those who met the eligibility criteria, these patients were treated with latanoprost 0.005% ophthalmic solution for 4 weeks. Peripapillary vessel density (VD) of radial peripapillary capillaries (RPC) layer, macular VD in both superficial and deep layers, and foveal avascular zone (FAZ) area were measured by optical coherence tomography angiography (OCTA) before and after the treatment. We compared the cha

SUBMITTER: Chen X 

PROVIDER: S-EPMC8695549 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature