A specific selenium-chelating peptide isolated from the protein hydrolysate of Grifola frondosa.

ABSTRACT: Background: Grifola frondosa is a type of edible medicinal mushroom with abundant proteins. Selenium (Se) is an essential micronutrient for human. Many animal experiments and clinical studies had indicated that Se plays an important role in diverse physiologic actions. Most inorganic selenium compounds are toxic, and the lowest lethal dose is relatively small. Peptide-Se chelate can probably be dietary supplements in functional foods for humans with Se deficiency. Methods: In this study, a specific tripeptide Arg-Leu-Ala (RLA) with strong Se-chelating capacity was purified from Grifola frondosa through ultrafiltration, reversed-phase HPLC and gel filtration chromatography. The UV, SEM, XRD, ¹H NMR spectra are shown to provide more information about ch

SUBMITTER: Xiong Y 

PROVIDER: S-EPMC8695590 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature