Prolonged exposure to continuous renal replacement therapy in patients with acute kidney injury.

ABSTRACT:

Background

Little is known about the process of deciding to discontinue continuous renal replacement therapy (CRRT) in patients with acute kidney injury (AKI) and the impact of CRRT duration on outcomes.

Methods

We report the clinical parameters of prolonged CRRT exposure and predictors of doubling of serum creatinine or need for dialysis at 90 days after CRRT with propensity score matching, including covariates that were likely to influence patients in the prolonged CRRT group.

Results

Among 104 survey responders, most use urine output (87%) to guide CRRT discontinuation, 24% use improvement in clinical or hemodynamic status. In the cohort study, of 854 included patients, 465 participated in the assessment of kidney recovery. Patients with prolonged CRRT had higher S

SUBMITTER: Shawwa K 

PROVIDER: S-EPMC8695624 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature