Mitochondrial-Respiration-Improving Effects of Three Different Gardeniae Fructus Preparations and Their Components.

ABSTRACT: The processing method for Chinese traditional herbal medicine is "Pao Zhi" in Chinese. This study examined the efficacy of the Pao Zhi on the preparations of Gardeniae Fructus (GF) on a mitochondrial respiratory function in rats. To determine the efficacy of Pao Zhi, we investigated the effects of GF heat processing on mitochondrial respiratory function. To test the GF components, the rats were randomly divided into a geniposide-alone group, crocin-alone group, and combination groups and treated with geniposide and crocin at different ratios. The results showed that a high dose, raw GF was more effective in improving the neurological function, mitochondrial respiratory function, and activities of Na⁺-K⁺-ATPase and Ca²⁺-Mg²⁺-ATPase than the prepar

SUBMITTER: Wang Y 

PROVIDER: S-EPMC8697009 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature