Long-Term Complications in Youth-Onset Type 2 Diabetes.

ABSTRACT:

Background

The prevalence of type 2 diabetes in youth is increasing, but little is known regarding the occurrence of related complications as these youths transition to adulthood.

Methods

We previously conducted a multicenter clinical trial (from 2004 to 2011) to evaluate the effects of one of three treatments (metformin, metformin plus rosiglitazone, or metformin plus an intensive lifestyle intervention) on the time to loss of glycemic control in participants who had onset of type 2 diabetes in youth. After completion of the trial, participants were transitioned to metformin with or without insulin and were enrolled in an observational follow-up study (performed from 2011 to 2020), which was conducted in two phases; the results of this follow-up study are reported here. Ass

SUBMITTER: TODAY Study Group 

PROVIDER: S-EPMC8697255 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature