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Dual C-H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone.

ABSTRACT: A rhodium-catalyzed, N-H free indole directed cyclization reaction of benzoquinone via a dual C-H activation strategy is disclosed. This protocol has a good functional group tolerance and affords useful indole-fused heterocylces. Besides, it is insensitive to moisture, commercially available solvent can be directly used and work quite well for this transformation.

SUBMITTER: Zhang Q

PROVIDER: S-EPMC8697334 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Dual C-H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone.

Zhang Qijing Q Li Qianrong Q Wang Chengming C

RSC advances 20210301 21

A rhodium-catalyzed, N-H free indole directed cyclization reaction of benzoquinone via a dual C-H activation strategy is disclosed. This protocol has a good functional group tolerance and affords useful indole-fused heterocylces. Besides, it is insensitive to moisture, commercially available solvent can be directly used and work quite well for this transformation. ...[more]

PMID: 35423833

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