In silico exploration of lignin peroxidase for unraveling the degradation mechanism employing lignin model compounds.

ABSTRACT: Lignin peroxidase is a heme-containing biocatalyst, well-known for its diverse applications in the fields from environmental chemistry to biotechnology. LiP-mediated oxidative catalysis is H₂O₂-dependent, and can oxidize phenolic, and non-phenolic substrates by oxidative cleavage of the C-C and C-O bonds of lignin. In contrast to fungi-derived LiP, the binding affinity of bacterial-derived LiP to lignin at the molecular level is poorly known to date. Tremendous wet-lab studies have been unveiled that provide degradation and biotransformation information on kraft lignin, whilst studies on the completely transformed compounds and the degradation of each transformed compounds simultaneously during degradation are scarce. To gain an understanding of the degradation proces

SUBMITTER: Singh AK 

PROVIDER: S-EPMC8697836 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature