Age and Body Condition Influence the Post-Prandial Interleukin-1β Response to a High-Starch Meal in Horses.

ABSTRACT: Older horses and those prone to obesity may be at a higher risk for inflammation than younger and leaner counterparts. Previous research indicated a postprandial elevation in plasma concentrations of interleukin-1β (IL-1β), a pro-inflammatory cytokine, after consuming 1.2 g of non-structural carbohydrates/kilogram of body weight. However, these studies utilized horses of mixed age and body condition. The current study evaluated post-prandial IL-1β concentrations in horses specifically comparing lean to over-conditioned and middle aged to older. Our results suggest that at least two weeks of daily consumption of a high non-structural carbohydrate diet is required to induce a post-prandial increase in IL-1β concentrations in younger and leaner horses. In opposition to this, older and over-co

SUBMITTER: Suagee-Bedore J 

PROVIDER: S-EPMC8698138 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature