Influence of Redox Stress on Crosstalk between Fibroblasts and Keratinocytes.

ABSTRACT: Although the skin is constantly subjected to endogenous and exogenous stress, it maintains a homeostatic state through wound repair and regeneration pathways. Treatment for skin diseases and injury requires a significant understanding of the various mechanisms and interactions that occur within skin cells. Keratinocytes and fibroblasts interact with each other and act as key players in the repair process. Although fibroblasts and keratinocytes are widely studied in wound healing and skin remodeling under different conditions, the influence of redox stress on keratinocyte-fibroblast crosstalk has not been thoroughly investigated. In this study, we used cold atmospheric plasma (CAP) to generate and deliver oxidative stress to keratinocytes and fibroblasts and to assess its impact on their in

SUBMITTER: Bhartiya P 

PROVIDER: S-EPMC8698713 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature