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Hyperspectral Imaging for the Evaluation of Microcirculatory Tissue Oxygenation and Perfusion Quality in Haemorrhagic Shock: A Porcine Study.


ABSTRACT:

Background

The ultimate goal of haemodynamic therapy is to improve microcirculatory tissue and organ perfusion. Hyperspectral imaging (HSI) has the potential to enable noninvasive microcirculatory monitoring at bedside.

Methods

HSI (Tivita® Tissue System) measurements of tissue oxygenation, haemoglobin, and water content in the skin (ear) and kidney were evaluated in a double-hit porcine model of major abdominal surgery and haemorrhagic shock. Animals of the control group (n = 7) did not receive any resuscitation regime. The interventional groups were treated exclusively with either crystalloid (n = 8) or continuous norepinephrine infusion (n = 7).

Results

Haemorrhagic shock led to a drop in tissue oxygenation parameters in all groups. These correlated with

SUBMITTER: Dietrich M 

PROVIDER: S-EPMC8698916 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature