Pharmacogenetics of Biological Agents Used in Inflammatory Bowel Disease: A Systematic Review.
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ABSTRACT:
SUBMITTER: Lauro R
PROVIDER: S-EPMC8699014 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
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Pharmacogenetics of Biological Agents Used in Inflammatory Bowel Disease: A Systematic Review.
Lauro Rita R Mannino Federica F Irrera Natasha N Squadrito Francesco F Altavilla Domenica D Squadrito Giovanni G Pallio Giovanni G Bitto Alessandra A
Biomedicines 20211123 12
Inflammatory Bowel Disease (IBD) comprises a group of disorders, in particular Crohn's disease (CD) and ulcerative colitis (UC), characterized by chronic inflammation affecting the gastrointestinal tract. The treatment of these conditions is primarily based on anti-inflammatory drugs, although the use of biological drugs with lower side effects quickly increased in the last decade. However, the presence of certain polymorphisms in the population may determine a different outcome in response to t ...[more]
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