Maximizing the Surface Sensitivity of LSPR Biosensors through Plasmon Coupling-Interparticle Gap Optimization for Dimers Using Computational Simulations.

ABSTRACT: The bulk and surface refractive index sensitivities of LSPR biosensors, consisting of coupled plasmonic nanosphere and nano-ellipsoid dimers, were investigated by simulations using the boundary element method (BEM). The enhancement factor, defined as the ratio of plasmon extinction peak shift of multi-particle and single-particle arrangements caused by changes in the refractive index of the environment, was used to quantify the effect of coupling on the increased sensitivity of the dimers. The bulk refractive index sensitivity (RIS) was obtained by changing the dielectric medium surrounding the nanoparticles, while the surface sensitivity was modeled by depositing dielectric layers on the nanoparticle in an increasing thickness. The results show that by optimizing the interparticle gaps fo

SUBMITTER: Bonyar A 

PROVIDER: S-EPMC8699530 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature