Maternal hypertensive disorders in pregnancy and early childhood cardiometabolic risk factors: The Generation R Study.

ABSTRACT: The objective of this study was to determine the associations between hypertensive disorders of pregnancy and early childhood cardiometabolic risk factors in the offspring. Therefore, 7794 women from the Generation Rotterdam Study were included, an ongoing population-based prospective birth cohort. Women with a hypertensive disorder of pregnancy were classified as such when they were affected by pregnancy induced hypertension, pre-eclampsia or the haemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome during pregnancy. Early childhood cardiometabolic risk factors were defined as the body mass index at the age of 2, 6, 12, 36 months and 6 years. Additionally, it included systolic blood pressure, diastolic blood pressure, total fat mass, cholesterol, triglycerides, insuli

SUBMITTER: Gootjes DV 

PROVIDER: S-EPMC8699579 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature