Weaving Mitochondrial DNA and Y-Chromosome Variation in the Panamanian Genetic Canvas.

ABSTRACT: The Isthmus of Panama was a crossroads between North and South America during the continent's first peopling (and subsequent movements) also playing a pivotal role during European colonization and the African slave trade. Previous analyses of uniparental systems revealed significant sex biases in the genetic history of Panamanians, as testified by the high proportions of Indigenous and sub-Saharan mitochondrial DNAs (mtDNAs) and by the prevalence of Western European/northern African Y chromosomes. Those studies were conducted on the general population without considering any self-reported ethnic affiliations. Here, we compared the mtDNA and Y-chromosome lineages of a new sample collection from 431 individuals (301 males and 130 females) belonging to either the general population, mixed gro

SUBMITTER: Rambaldi Migliore N 

PROVIDER: S-EPMC8702192 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature