Predictors of secondary HIV transmission risk in a cohort of adolescents living with HIV in South Africa.

ABSTRACT:

Objective

Preventing secondary HIV transmission from adolescents and young people living with HIV (AYPLHIV) to their partners and children is critical to interrupting the HIV infection cycle in sub-Saharan Africa. We investigated predictors of secondary HIV transmission risk (past-year sexual risk combined with past-year viremia) among AYPLHIV in South Africa.

Design

A prospective cohort of AYLPHIV in South Africa recruited n = 1046 participants in 2014-2015, 93.6% of whom were followed up in 2016-2017 (1.5% mortality). Questionnaires used validated scales where available and biomarkers were extracted from n = 67 health facilities.

Methods

Multivariate logistic regressions tested baseline factors associated with secondary HIV transmission risk, controlling for covaria

SUBMITTER: Toska E 

PROVIDER: S-EPMC8702447 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature