Association Between the Severity of Diabetic Retinopathy and Optical Coherence Tomography Angiography Metrics.

ABSTRACT: Diabetic retinopathy, the most serious ocular complication of diabetes, imposes a serious economic burden on society. Automatic and objective assessment of vessel changes can effectively manage diabetic retinopathy and prevent blindness. Optical coherence tomography angiography (OCTA) metrics have been confirmed to be used to assess vessel changes. The accuracy and reliability of OCTA metrics are restricted by vessel segmentation methods. In this study, a multi-branch retinal vessel segmentation method is proposed, which is comparable to the segmentation results obtained from the manual segmentation, effectively extracting vessels in low contrast areas and improving the integrity of the extracted vessels. OCTA metrics based on the proposed segmentation method were validated to be reliable

SUBMITTER: Xu B 

PROVIDER: S-EPMC8702651 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature