Medication Discrepancies and Regimen Complexity in Decompensated Cirrhosis: Implications for Medication Safety.

ABSTRACT: Discrepancies between the medicines consumed by patients and those documented in the medical record can affect medication safety. We aimed to characterize medication discrepancies and medication regimen complexity over time in a cohort of outpatients with decompensated cirrhosis, and evaluate the impact of pharmacist-led intervention on discrepancies and patient outcomes. In a randomized-controlled trial (n = 57 intervention and n = 57 usual care participants), medication reconciliation and patient-oriented education delivered over a six-month period was associated with a 45% reduction in the incidence rate of 'high' risk discrepancies (IRR = 0.55, 95%CI = 0.31-0.96) compared to usual care. For each additional 'high' risk discrepancy at baseline, the odds of having ≥ 1 unplanned medication

SUBMITTER: Hayward KL 

PROVIDER: S-EPMC8703811 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature