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It More than Adds Up: Interaction of Antibiotic Mixing and Temperature.


ABSTRACT: Use of antibiotics for the treatment and prevention of bacterial infections in humans, agri- and aquaculture as well as livestock rearing leads to antibiotic pollution of fresh water and these antibiotics have an impact on free-living bacteria. While we know which antibiotics are most common in natural environments such as rivers and streams, there is considerable uncertainty regarding antibiotics' interactions with one another and the effect of abiotic factors such as temperature. Here, we used an experimental approach to explore the effects of antibiotic identity, concentration, mixing and water temperature on the growth of Pseudomonas fluorescens, a common, ubiquitous bacterium. We exposed P. fluorescens to the four antibiotics most commonly found in surface waters (ciprof

SUBMITTER: Danner MC 

PROVIDER: S-EPMC8703992 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature