Effects of surgery on survival of patients aged 75 years or older with Merkel cell carcinoma.

ABSTRACT:

Objective

To investigate whether surgery improves prognosis in elderly patients with Merkel cell carcinoma (MCC).

Materials/methods

Data of all patients with MCC diagnosed between 2004 and 2015 were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Differences in baseline characteristics were analyzed among the age groups (75-80, 80-85, and ≥85 years). Multivariate Cox proportional hazards analysis was used to assess the effects of each variable on patient outcomes. The Kaplan-Meier curves were employed to evaluate MCC overall survival (OS) and MCC-specific survival (MSS).

Results

A total of 1156 of patients with MCC met the inclusion and exclusion criteria. The surgery rate decreased with age (75-80, 80-85, and ≥85 years were 93.3%, 91.1

SUBMITTER: Ren K 

PROVIDER: S-EPMC8704145 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature