Current landscape and future perspectives in preclinical MR and PET imaging of brain metastasis.

ABSTRACT: Brain metastasis (BM) is a major cause of cancer patient morbidity. Clinical magnetic resonance imaging (MRI) and positron emission tomography (PET) represent important resources to assess tumor progression and treatment responses. In preclinical research, anatomical MRI and to some extent functional MRI have frequently been used to assess tumor progression. In contrast, PET has only to a limited extent been used in animal BM research. A considerable culprit is that results from most preclinical studies have shown little impact on the implementation of new treatment strategies in the clinic. This emphasizes the need for the development of robust, high-quality preclinical imaging strategies with potential for clinical translation. This review focuses on advanced preclinical MRI and PET imag

SUBMITTER: Aasen SN 

PROVIDER: S-EPMC8704384 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature