Comparison of the airway microbiota in children with chronic suppurative lung disease.

ABSTRACT:

Rationale

The airway microbiota is important in chronic suppurative lung diseases, such as primary ciliary dyskinesia (PCD) and cystic fibrosis (CF). This comparison has not previously been described but is important because difference between the two diseases may relate to the differing prognoses and lead to pathological insights and potentially, new treatments.

Objectives

To compare the longitudinal development of the airway microbiota in children with PCD to that of CF and relate this to age and clinical status.

Methods

Sixty-two age-matched children (age range 0.5-17 years) with PCD or CF (n=31 in each group) were recruited prospectively and followed for 1.1 years. Throat swabs or sputum as well as clinical information were collected at routine clinical appointmen

SUBMITTER: Ahmed B 

PROVIDER: S-EPMC8705203 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature