Diversity of Human-Associated Bifidobacterial Prophage Sequences.

ABSTRACT: Members of Bifidobacterium play an important role in the development of the immature gut and are associated with positive long-term health outcomes for their human host. It has previously been shown that intestinal bacteriophages are detected within hours of birth, and that induced prophages constitute a significant source of such gut phages. The gut phageome can be vertically transmitted from mother to newborn and is believed to exert considerable selective pressure on target prokaryotic hosts affecting abundance levels, microbiota composition, and host characteristics. The objective of the current study was to investigate prophage-like elements and predicted CRISPR-Cas viral immune systems present in publicly available, human-associated Bifidobacterium genomes. Analysis of 585 fully sequ

SUBMITTER: Buckley D 

PROVIDER: S-EPMC8705816 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature