Hydrolytic Degradation of Polylactic Acid Fibers as a Function of pH and Exposure Time.

ABSTRACT: Polylactic acid (PLA) is a widely used bioresorbable polymer in medical devices owing to its biocompatibility, bioresorbability, and biodegradability. It is also considered a sustainable solution for a wide variety of other applications, including packaging. Because of its widespread use, there have been many studies evaluating this polymer. However, gaps still exist in our understanding of the hydrolytic degradation in extreme pH environments and its impact on physical and mechanical properties, especially in fibrous materials. The goal of this work is to explore the hydrolytic degradation of PLA fibers as a function of a wide range of pH values and exposure times. To complement the experimental measurements, molecular-level details were obtained using both molecular dynamics (MD) simulat

SUBMITTER: Vaid R 

PROVIDER: S-EPMC8706057 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature