Ontology highlight
ABSTRACT:
SUBMITTER: Katina N
PROVIDER: S-EPMC8706126 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Katina Natalia N Mikhaylina Alisa A Ilina Nelly N Eliseeva Irina I Balobanov Vitalii V
Molecules (Basel, Switzerland) 20211215 24
The formation of amyloid fibrils is one of the variants of the self-organization of polypeptide chains. For the amyloid aggregation, the solution must be oversaturated with proteins. The interface of the liquid (solution) and solid (vessel walls) phases can trigger the adsorption of protein molecules, and the resulting oversaturation can initiate conformational transitions in them. In any laboratory experiment, we cannot exclude the presence of surfaces such as the walls of vessels, cuvettes, et ...[more]