Assessment of Changes in the Oral Microbiome That Occur in Dogs with Periodontal Disease.

ABSTRACT: The oral microbiome in dogs is a complex community. Under some circumstances, it contributes to periodontal disease, a prevalent inflammatory disease characterized by a complex interaction between oral microbes and the immune system. Porphyromonas and Tannerella spp. are usually dominant in this disease. How the oral microbiome community is altered in periodontal disease, especially sub-dominant microbial populations is unclear. Moreover, how microbiome functions are altered in this disease has not been studied. In this study, we compared the composition and the predicted functions of the microbiome of the cavity of healthy dogs to those with from periodontal disease. The microbiome of both groups clustered separately, indicating important differences. Periodontal disease resulted in a sig

SUBMITTER: Santibanez R 

PROVIDER: S-EPMC8707289 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature