Mitochondria and Their Relationship with Common Genetic Abnormalities in Hematologic Malignancies.
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ABSTRACT:
SUBMITTER: Czegle I
PROVIDER: S-EPMC8707674 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Publications
Mitochondria and Their Relationship with Common Genetic Abnormalities in Hematologic Malignancies.
Czegle Ibolya I Gray Austin L AL Wang Minjing M Liu Yan Y Wang Jun J Wappler-Guzzetta Edina A EA
Life (Basel, Switzerland) 20211207 12
Hematologic malignancies are known to be associated with numerous cytogenetic and molecular genetic changes. In addition to morphology, immunophenotype, cytochemistry and clinical characteristics, these genetic alterations are typically required to diagnose myeloid, lymphoid, and plasma cell neoplasms. According to the current World Health Organization (WHO) Classification of Tumors of Hematopoietic and Lymphoid Tissues, numerous genetic changes are highlighted, often defining a distinct subtype ...[more]
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