Epidemiology and Molecular Transmission Characteristics of HIV in the Capital City of Anhui Province in China.

ABSTRACT: Hefei, Anhui province, is one of the cities in the Yangtze River Delta, where many people migrate to Jiangsu, Zhejiang and Shanghai. High migration also contributes to the HIV epidemic. This study explored the HIV prevalence in Hefei to provide a reference for other provinces and assist in the prevention and control of HIV in China. A total of 816 newly reported people with HIV in Hefei from 2017 to 2020 were recruited as subjects. HIV subtypes were identified by a phylogenetic tree. The most prevalent subtypes were CRF07_BC (41.4%), CRF01_AE (38.1%) and CRF55_01B (6.3%). Molecular networks were inferred using HIV-TRACE. The largest and most active transmission cluster was CRF55_01B in Hefei's network. A Chinese national database (50,798 sequences) was also subjected to molecular network a

SUBMITTER: Zheng S 

PROVIDER: S-EPMC8708547 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature