Vaccine Technologies and Platforms for Infectious Diseases: Current Progress, Challenges, and Opportunities.

ABSTRACT: Vaccination is a key component of public health policy with demonstrated cost-effective benefits in protecting both human and animal populations. Vaccines can be manufactured under multiple forms including, inactivated (killed), toxoid, live attenuated, Virus-like Particles, synthetic peptide, polysaccharide, polysaccharide conjugate (glycoconjugate), viral vectored (vector-based), nucleic acids (DNA and mRNA) and bacterial vector/synthetic antigen presenting cells. Several processes are used in the manufacturing of vaccines and recent developments in medical/biomedical engineering, biology, immunology, and vaccinology have led to the emergence of innovative nucleic acid vaccines, a novel category added to conventional and subunit vaccines. In this review, we have summarized recent advance

SUBMITTER: Ghattas M 

PROVIDER: S-EPMC8708925 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature