Lipids in Pathophysiology and Development of the Membrane Lipid Therapy: New Bioactive Lipids.

ABSTRACT: Membranes are mainly composed of a lipid bilayer and proteins, constituting a checkpoint for the entry and passage of signals and other molecules. Their composition can be modulated by diet, pathophysiological processes, and nutritional/pharmaceutical interventions. In addition to their use as an energy source, lipids have important structural and functional roles, e.g., fatty acyl moieties in phospholipids have distinct impacts on human health depending on their saturation, carbon length, and isometry. These and other membrane lipids have quite specific effects on the lipid bilayer structure, which regulates the interaction with signaling proteins. Alterations to lipids have been associated with important diseases, and, consequently, normalization of these alterations or regulatory interv

SUBMITTER: Torres M 

PROVIDER: S-EPMC8708953 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature