Genome and Metabolome MS-Based Mining of a Marine Strain of Aspergillus affinis.

ABSTRACT: Aspergillus section Circumdati encompasses several species that express both beneficial (e.g., biochemical transformation of steroids and alkaloids, enzymes and metabolites) and harmful compounds (e.g., production of ochratoxin A (OTA)). Given their relevance, it is important to analyze the genetic and metabolic diversity of the species of this section. We sequenced the genome of Aspergillus affinis CMG 70, isolated from sea water, and compared it with the genomes of species from section Circumdati, including A. affinis's strain type. The A. affinis genome was characterized considering secondary metabolites biosynthetic gene clusters (BGCs), carbohydrate-active enzymes (CAZymes), and transporters. To uncover the biosynthetic potential of A. affi

SUBMITTER: Goncalves MFM 

PROVIDER: S-EPMC8709101 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature