Real-world evidence of age-independent electroconvulsive therapy efficacy: A retrospective cohort study.

ABSTRACT:

Objectives

Electroconvulsive therapy (ECT) is an effective treatment for depressive disorders and approved for use in adolescents and adults, but it is unclear whether efficacy or cognitive side effect burden differs with age or if effectiveness in usual clinical practice matches that in prospective studies. We examined the effects of ECT on depression and cognition in a large clinical cohort.

Methods

A retrospective cohort study of patients ages 16 and older receiving ECT between 2011 and 2020 and who were evaluated with the Quick Inventory of Depressive Symptomatology (QIDS), the Behavior and Symptom Identification Scale-24 (BASIS-24), and the Montreal Cognitive Assessment (MoCA) at baseline and after treatment #10.

Results

Among 1698 patients, ECT was associated wi

SUBMITTER: Luccarelli J 

PROVIDER: S-EPMC8709695 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature