A journey through the Corynebacterium pseudotuberculosis proteome promotes insights into its functional genome.

ABSTRACT:

Background

Corynebacterium pseudotuberculosis is a Gram-positive facultative intracellular pathogen and the etiologic agent of illnesses like caseous lymphadenitis in small ruminants, mastitis in dairy cattle, ulcerative lymphangitis in equines, and oedematous skin disease in buffalos. With the growing advance in high-throughput technologies, genomic studies have been carried out to explore the molecular basis of its virulence and pathogenicity. However, data large-scale functional genomics studies are necessary to complement genomics data and better understating the molecular basis of a given organism. Here we summarize, MS-based proteomics techniques and bioinformatics tools incorporated in genomic functional studies of C. pseudotuberculosis to discover the differen

SUBMITTER: Marques da Silva W 

PROVIDER: S-EPMC8710256 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature