Cardiac resynchronization therapy with multipoint pacing via quadripolar lead versus traditional biventricular pacing: A systematic review and meta-analysis of clinical studies on hemodynamic, clinical, and prognostic parameters.

ABSTRACT:

Background

Cardiac resynchronization therapy (CRT) is one of the cornerstones of heart failure (HF) therapy, as it has reduced mortality and morbidity and has shown improvement in functional capacity. Multipoint pacing (MPP) is a way of configuring CRT with the aim to improve the percentage of patients who respond to CRT.

Objective

To demonstrate the effectiveness of the MPP compared to traditional biventricular pacing (BiV).

Methods

We performed a systematic review and meta-analysis according to PRISMA guidelines of studies in which MPP vs BiV strategy were compared.

Results

MPP use is associated with a higher rate of patients experiencing functional improvement (odds ratio: 2.51, 95% confidence interval [CI], 1.56-4.06; P = .0002) and with higher delta

SUBMITTER: Massacesi C 

PROVIDER: S-EPMC8710588 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature